Synthetic Chemistry
Research and Development (R&D) plays a critical role in helping companies stay competitive by creating new and innovative products, improving existing ones, and developing more efficient and sustainable manufacturing processes.
To achieve these goals, our R&D teams often employ a wide range of tools and techniques, including laboratory experiments, computer simulations, and data analysis. we also collaborate with academic researchers, industry partners, and other stakeholders to share knowledge and expertise.
Overall, the goal of our R&D is to drive innovation and help companies stay at the forefront of their respective industries. This requires a combination of creativity, scientific rigor, and practical know-how to turn promising ideas into successful products that meet the needs of customers and stakeholders.
At Harmoni Analyticals, well experienced scientific team delivering the projects based on customer requirement. Our team works on developing innovative ideas, methodologies and chemistry to deliver cost effective and safe process for new products development.
Our Capabilities
- Process Development of API/ Technical/ Intermediates
- Synthesis of molecules with a completely new structure
- Synthesis of special reagents, intermediates, and molecular fragments
- Preparation of API or related substances Synthesis of standard substances
- Synthesis design and preparation of impurities or metabolites
- Synthesis and resolution of chiral compounds
- Synthesis of reference compounds, intermediates, building blocks, novel scaffolds, NCEs, analogues for Lead Optimisation & focused libraries of up to 50 compounds
- Custom Synthesis
- MG to KG Scale
We Do
- Smartest Synthetic Routes / Schemes Development
- Metal Mediated Coupling Reactions: Pd, Cu, Ni, Mg, Li
- Peptide Coupling reactions, Acylation, Alkylation, Urea, Reduction, Oxidation, Reductive Amination, Mitsunobu, Friedel-Crafts, Wittig, Cyanation & Fluorine Chemistry
- Nucleoside Nucleotide Chemistry
- Carbohydrate Chemistry, Heterocyclic Chemistry
- Chiral Chemistry / Asymmetric Synthesis
- Electronic Materials Chemistry
- Autoclave and Hydrogenation
Business Models
At Harmoni Analyticals, we offer a range of cost-effective service models for synthetic chemistry, including:
- Dedicated Full-Time Employees
- Flexibility to increase or decrease team size
- Flexibility to reprioritize targets/ project direction
Full Time Equivalent Model (FTE)
The FTE model is ideal for projects where a significant degree of troubleshooting will be required
- Fixed price quoted for the amount of specific synthesis of a molecule, series of molecules, or small library
- Fixed price quoted for a specific service (e.g. chiral separation, fragment-based screening)
- Literature precedent is very important for an accurate quotation
- Non-GMP up to kilo scale available
Fee For Service Model (FFS)
The FFS model ideal for projects with known or well understood chemistry
We Offer
- Flexible & Client Driven Services
- Realistic Pricing & Timeline
Infrastructure
- Lab space >2500 sq. ft., walk-in fume hoods and bench top fume hoods
- 50 ml to 50 lit glass reactors
Instrumentation
- Prep-HPLC System
- HPLCs with PDA Detector
- GC with FID
- Rotary Evaporator
- KFR Titrator
- FT-IR
- Melting Range Apparatus
