Analytical Chemistry
Harmoni Analyticals offering entire gamut of analytical studies required for crop protection agents and industrial chemicals to meet the global regulatory requirement as per OECD, EEC, ICH, ABNT NBR, AOAC, SANCO, OPPTS (OCSPP), EPA, WHO, FAO, CIPAC, CIB_RC, BIS, EU and other guidelines to enable US-EPA, EU, Brazilian, Mexican, Australian, Canadian, Indian and other global submissions.
Some of the key areas but not limited to
- Residue & Persistence Studies
- Five Batch Analysis
- Storage Stability
- Physical and Chemical Properties (Technical / Formulations)
- Environmental Fate Studies
Our expert team will provide the best service at reasonable cost and quick turnaround time.
Residue & Persistence Studies
Residue chemistry plays a critical role in the development of any plant protection product essential for agrochemical companies when pursuing registration, or re-registration, of crop protection products.
At Harmoni Analyticals, we offer laboratory phases of residue studies (method development, validation and quantification of pesticide residues and its metabolites) in following matrices by using high end technology
- Plant Soil Water Air
Five Batch Analysis
At Harmoni Analyticals, we are offering complete solution for five batch analysis from pre-screening, impurities synthesis/separation, validation and quantification of impurities in 5 batches along with technical. Few highlights are as follows
- Pre-screening of 5-batches for impurities including 3D screening
- Impurity identification and structure elucidation in consultation with the sponsor
- Isolation/synthesis of impurities required for 5-batch analysis
- GLP analysis of 5-batches using validated analytical methods for active ingredient content and impurities
- Characterization of 5 commercial batches along with reference standards by UV, IR, NMR, LC-MS/MS and/or GC-MS as applicable.
Storage Stability
At Harmoni Analyticals, our scientific team conduct different types of storage stability studies based on type of formulation and regulatory requirements. The storage stability and shelf life of a product can be determined under a variety of specified storage conditions:
- Low Temperature Storage Stability
- Freeze-Thaw Stability
- Accelerated
- Real Time
- Multi-Location
- Long Term Storage Stability with Corrosion Characteristics
Physical and Chemical Properties
(Technical / Formulations)
At Harmoni Analyticals, we offer characterization and physicochemical testing studies necessary to support registrations worldwide. Physicochemical testing is an integral requirement of product registrations and approvals for agrochemicals, biocides, chemicals, pharmaceuticals, and animal health products.
- Appearance, colour, odour, physical state
- Acidity, alkalinity or pH value
- Bulk Density (solids)
- Density or specific gravity (liquids)
- Viscosity and surface tension (liquids)
- Relevant characteristics applicable to the particular formulation type (for example for wettable powder: suspensibility, wet sieve test, wettability and persistent foam)
- Flash Point
- Flammability
- Explosive Properties
- Oxidising Properties
- Corrosive Hazard
- Melting Point/ Boiling point/ Freezing point
- Solubility in Water / Organic Solvents
- UV-Visible absorption spectra
- Dissociation Constant
- Vapour Pressure
- Spontaneity of Dispersion
- Chemical Incompatibility (Oxidation/ Reduction)
- Container Content Compatibility
- Corrosively/ Corrosiveness
- Suspensibility
- Photolysis Characteristics
- Stability to Metals, Metal Ions & Elevated Temperature
- Emulsion Stability
- Surface Tension
- Moisture Content
- Pourability
- Persistence Foam
- Weight Loss on Heating
- Residue on Ignition
- Sieve Analysis
- Density/ Specific Gravity
- Partition Coefficient
- Viscosity
- Solution Stability
- Molar Absorption Coefficient
- Screening for Explosive or Self-Reactive Properties
Environmental Fate Studies
Environmental fate studies document product’s behaviour in the environment after application. EFate data shows how product exposure and its degradation in soil, sediment, water, groundwater, and air. The following are different types of Efate studies required for registration of crop protection products:
- Adsorption / Desorption Study on Soil
- Rate of Degradation on Soil (Aerobic and Anaerobic) and Metabolism
- Rate of Degradation on Sediments and Metabolism
- Hydrolysis and Photolysis in Water
- High Temperature Hydrolysis
-
Soil Microorganisms:
Nitrogen Transformation Test
-
Soil Microorganisms:
Carbon Transformation Test - Mobility in Soil
- Activated Sludge/ Microbial Activity
- Aerobic/ Anaerobic Degradation
- Soil, Plant and Animal Metabolism
- Soil Adsorption and Desorption
- Hydrolysis and Photolysis
- Leaching
